先上代码：

 <DataGrid Name="DGV" AutoGenerateColumns="False"  Grid.Row="0" Grid.Column="0"   HorizontalGridLinesBrush="RoyalBlue" VerticalGridLinesBrush="Tomato" CanUserAddRows="False" LoadingRow="dataGrid_LoadingRow"><DataGrid.ColumnHeaderStyle><Style TargetType="DataGridColumnHeader"><Setter Property="HorizontalContentAlignment" Value="Center"></Setter></Style></DataGrid.ColumnHeaderStyle> <DataGrid.Columns><DataGridTemplateColumn  Width="55" Header="序号"><DataGridTemplateColumn.CellTemplate><DataTemplate><TextBlock Text="{Binding RelativeSource={RelativeSource Mode=FindAncestor,AncestorType={x:Type DataGridRow}}, Path=Header}" HorizontalAlignment="Left" VerticalAlignment="Center" Margin="10,0,0,0"></TextBlock></DataTemplate></DataGridTemplateColumn.CellTemplate></DataGridTemplateColumn><!--<DataGridTemplateColumn  IsReadOnly="True" MinWidth="60"  Width="80" Header="编号"><DataGridTemplateColumn.CellTemplate><DataTemplate><TextBlock Text="{Binding Id}" TextTrimming="CharacterEllipsis"  HorizontalAlignment="Center"  FontSize="14"  Margin="3" TextWrapping="Wrap"></TextBlock></DataTemplate></DataGridTemplateColumn.CellTemplate></DataGridTemplateColumn>--><DataGridTemplateColumn  IsReadOnly="True" MinWidth="120"    Width="*" Header="牌位类型"><DataGridTemplateColumn.CellTemplate><DataTemplate><TextBlock Text="{Binding PaiweiType}" TextTrimming="CharacterEllipsis" FontSize="14" VerticalAlignment="Center"   Margin="3" TextWrapping="Wrap"></TextBlock></DataTemplate></DataGridTemplateColumn.CellTemplate></DataGridTemplateColumn><DataGridTemplateColumn  IsReadOnly="True" MinWidth="80"  Width="*" Header="牌位种类"><DataGridTemplateColumn.CellTemplate><DataTemplate><TextBlock Text="{Binding DaxiaoSuixi}" TextTrimming="CharacterEllipsis"   HorizontalAlignment="Center"  FontSize="14"  Margin="3" TextWrapping="Wrap"></TextBlock></DataTemplate></DataGridTemplateColumn.CellTemplate></DataGridTemplateColumn><DataGridTemplateColumn  IsReadOnly="True" MinWidth="80"  Width="*" Header="金额"><DataGridTemplateColumn.CellTemplate><DataTemplate><TextBlock Text="{Binding JinE}" TextTrimming="CharacterEllipsis"   HorizontalAlignment="Center"  FontSize="14"  Margin="3" TextWrapping="Wrap"></TextBlock></DataTemplate></DataGridTemplateColumn.CellTemplate></DataGridTemplateColumn></DataGrid.Columns></DataGrid>

序号列：

  <DataGridTemplateColumn  Width="55" Header="序号"><DataGridTemplateColumn.CellTemplate><DataTemplate><TextBlock Text="{Binding RelativeSource={RelativeSource Mode=FindAncestor,AncestorType={x:Type DataGridRow}}, Path=Header}" HorizontalAlignment="Left" VerticalAlignment="Center" Margin="10,0,0,0"></TextBlock></DataTemplate></DataGridTemplateColumn.CellTemplate></DataGridTemplateColumn>

需要使用 创建row事件

LoadingRow="dataGrid_LoadingRow"

事件操作为：

 private void dataGrid_LoadingRow(object sender, DataGridRowEventArgs e){e.Row.Header = e.Row.GetIndex() + 1;}

显示效果如下：

这个时候需要讲RowHeader去掉就可以了（未找到方法的话，可以使用宽度为0）。

RowHeaderWidth="0"

还有个方法就是直接写死：

<DataGrid><DataGrid.RowHeaderStyle><Style TargetType="DataGridRowHeader"><Setter Property="Content" Value="{Binding RelativeSource={RelativeSource Mode=Self}, Path=Row.Index}"/></Style></DataGrid.RowHeaderStyle><!-- 其他DataGrid设置和内容 -->
</DataGrid>